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TargetMu-type opioid receptor
LigandBDBM179903
Substrate/Competitorn/a
Meas. Tech.Opioid Receptor Binding Assay
Ki 0.100±n/a nM
Citation Blumberg, LCDeaver, DREyerman, DJWynn, TA Methods for treating depressive symptoms US Patent US10231963 Publication Date 3/19/2019
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Mu-type opioid receptor
Synonyms:M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44789.51
Organism:Homo sapiens (Human)
Description:P35372
Residue:400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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  Blast E-value cutoff:
BDBM179903
n/a
NameBDBM179903
Synonyms:US10231963, Table C.7 | US10287250, Compound D.7 | US10736890, Compound TABLE C.7 | US10752592, Compound TABLE D.7 | US11534436, Compound Table C.7 | US9133125, Table D, Compound 7 | US9656961, Example 00171
TypeSmall organic molecule
Emp. Form.C21H28N2O
Mol. Mass.324.4598
SMILESNC(=O)c1ccc2C[C@@H]3C4CCCC[C@]4(CCN3CC3CC3)c2c1 |r|
Structure
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