| Reaction Details |
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 | Report a problem with these data |
| Target | D-amino-acid oxidase |
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| Ligand | BDBM23171 |
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| Substrate/Competitor | BDBM23167 |
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| Meas. Tech. | In vitro D-Amino Acid Oxidase Assay |
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| pH | 8.5±n/a |
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| Temperature | 295.15±n/a K |
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| IC50 | 1510±120 nM |
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| Citation |  Ferraris, D; Duvall, B; Ko, YS; Thomas, AG; Rojas, C; Majer, P; Hashimoto, K; Tsukamoto, T Synthesis and Biological Evaluation of d-Amino Acid Oxidase Inhibitors. J Med Chem51:3357-9 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Inhibition_Run data, Solution Info, Assay Method |
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| D-amino-acid oxidase |
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| Name: | D-amino-acid oxidase |
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| Synonyms: | D-Amino Acid Oxidase (DAAO) | D-amino-acid oxidase (DAAO) | DAMOX | DAO | OXDA_PIG |
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| Type: | Flavoprotein |
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| Mol. Mass.: | 39338.01 |
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| Organism: | Sus scrofa (pig) |
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| Description: | Homodimer. |
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| Residue: | 347 |
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| Sequence: | MRVVVIGAGVIGLSTALCIHERYHSVLQPLDVKVYADRFTPFTTTDVAAGLWQPYTSEPS
NPQEANWNQQTFNYLLSHIGSPNAANMGLTPVSGYNLFREAVPDPYWKDMVLGFRKLTPR
ELDMFPDYRYGWFNTSLILEGRKYLQWLTERLTERGVKFFLRKVESFEEVARGGADVIIN
CTGVWAGVLQPDPLLQPGRGQIIKVDAPWLKNFIITHDLERGIYNSPYIIPGLQAVTLGG
TFQVGNWNEINNIQDHNTIWEGCCRLEPTLKDAKIVGEYTGFRPVRPQVRLEREQLRFGS
SNTEVIHNYGHGGYGLTIHWGCALEVAKLFGKVLEERNLLTMPPSHL
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| BDBM23171 |
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| BDBM23167 |
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| Name | BDBM23171 |
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| Synonyms: | 5-iodo-1,2-benzoxazol-3-ol | Benzo[d]isoxazol-3-ol Derivative, 3d |
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| Type | Small organic molecule |
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| Emp. Form. | C7H4INO2 |
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| Mol. Mass. | 261.0166 |
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| SMILES | Ic1ccc2o[nH]c(=O)c2c1 |
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| Structure | 
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