| Reaction Details |
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 | Report a problem with these data |
| Target | Malate dehydrogenase, mitochondrial |
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| Ligand | BDBM23222 |
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| Substrate/Competitor | BDBM23230 |
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| Meas. Tech. | Lactate Dehydrogenase Inhibition Assay |
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| IC50 | >2000000±n/a nM |
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| Citation |  Choi, SR; Pradhan, A; Hammond, NL; Chittiboyina, AG; Tekwani, BL; Avery, MA Design, synthesis, and biological evaluation of Plasmodium falciparum lactate dehydrogenase inhibitors. J Med Chem50:3841-50 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Malate dehydrogenase, mitochondrial |
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| Name: | Malate dehydrogenase, mitochondrial |
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| Synonyms: | MDH2 | MDHM_PIG | Malate dehydrogenase mitochondrial |
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| Type: | Oxidoreductase; homodimer |
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| Mol. Mass.: | 35493.48 |
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| Organism: | Sus scrofa (pig) |
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| Description: | Porcine heart mitochondria. |
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| Residue: | 337 |
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| Sequence: | MLSALARPAGAALRRSFSTSQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHT
PGVAADLSHIETRATVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIV
ATLTAACAQHCPDAMICIISNPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANAFV
AELKGLDPARVSVPVIGGHAGKTIIPLISQCTPKVDFPQDQLSTLTGRIQEAGTEVVKAK
AGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETDCPYFSTPLLLGKKGIEK
NLGIGKISPFEEKMIAEAIPELKASIKKGEEFVKNMK
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| BDBM23222 |
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| BDBM23230 |
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| Name | BDBM23222 |
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| Synonyms: | Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Acid | carbamoylformic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C2H3NO3 |
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| Mol. Mass. | 89.0501 |
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| SMILES | NC(=O)C(O)=O |
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| Structure | 
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