| Reaction Details |
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 | Report a problem with these data |
| Target | Aryl hydrocarbon receptor |
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| Ligand | BDBM23944 |
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| Substrate/Competitor | BDBM23927 |
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| Meas. Tech. | In Vitro Binding Assay |
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| pH | 7.6±n/a |
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| Temperature | 277.15±n/a K |
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| Ki | 60±3.2 nM |
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| Comments | Antagonist. |
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| Citation |  de Medina, P; Casper, R; Savouret, JF; Poirot, M Synthesis and biological properties of new stilbene derivatives of resveratrol as new selective aryl hydrocarbon modulators. J Med Chem48:287-91 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Aryl hydrocarbon receptor |
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| Name: | Aryl hydrocarbon receptor |
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| Synonyms: | AHR | AHR_RABIT | Aryl Hydrocarbon Receptor (AhR) | Dioxin receptor |
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| Type: | Transcription factor |
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| Mol. Mass.: | 94428.00 |
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| Organism: | Oryctolagus cuniculus (rabbit) |
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| Description: | Cytosols from rabbit liver were used in binding assay. |
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| Residue: | 847 |
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| Sequence: | MNGGGANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDV
INKLDKLSVLRLSVSYLRAKSFFDVALKSSSADRNGGQDPCRAKFGEGLNLQEGEFLLQA
LNGFVLVVTVDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPS
QCTDPGQGADETHGLPQPVYYNPDQLPPENSSFMERCFICRLRCLLDNSSGFLAMNFQGR
LKFLHGQNKKGKDGSLLPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPTGCDA
KGQIVLGYTEAELCMRGSGYQFIHAADMLYCAESHIRMIKTGESGLAVFRLLTKDNRWAW
VQSNARFIYKNGRPDFIIATQRPLTDEEGREHLLKRNTKLPFMFTTGEAVLYEMTSPFPP
IMDPLPIRPKSGTCGKDSATKPTPSKDSVHPSSLLSALMQQDESIYLYPPSSNAPFERNF
FTESLNECSNWPENVASVAGGSVLKHEQIGQSQEVSPAFSGDQTVLFPDNKNCDLYNIMK
NLGVDFEDIKNMQNEEFFGADFSGEVDFRDIDITDEILTYVQDSLNKSPFGSPGYQPQPA
TALNSSCMVQERLQLGPPQQPPCRSEQATVEPQQQLCQKMEHMQVNSMFANWSANQPVPF
SEPQQDLQPYSVFTDFHTADQAFPYTAAMNTMPYTQNFTPCNQTVAPQHSRCTQLDFAMG
NFDSSPYPSTSNLEDFVTCLQVPDRQTHGGNPQSAMVAPQTCYAGAVSMYQCQPGPAHTL
MGQMQCEPPVPGPEAFLNKFPNGGMLNETYPADLHDINNTVASTHLPPLHHPSEARPFPD
LASGRLL
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| BDBM23944 |
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| BDBM23927 |
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| Name | BDBM23944 |
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| Synonyms: | 1,3-bis(trifluoromethyl)-5-[(Z)-2-[4-(trifluoromethyl)phenyl]ethenyl]benzene | cis-Stilbene Derivative, 5e |
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| Type | Small organic molecule |
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| Emp. Form. | C17H9F9 |
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| Mol. Mass. | 384.239 |
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| SMILES | FC(F)(F)c1ccc(\C=C/c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1 |
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| Structure | 
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