| Reaction Details |
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 | Report a problem with these data |
| Target | Coagulation factor X |
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| Ligand | BDBM387050 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Assay |
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| Ki | <10±n/a nM |
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| Citation |  Ding, Z; Lai, G; Chen, S; Yan, X Hydrazine compound as blood coagulation factor Xa inhibitor US Patent US9938272 Publication Date 4/10/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Coagulation factor X |
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| Name: | Coagulation factor X |
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| Synonyms: | Coagulation factor X precursor | F10 | FA10_RAT | Factor Xa (fXa) | Stuart factor |
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| Type: | Enzyme |
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| Mol. Mass.: | 54255.03 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 482 |
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| Sequence: | MESPVRLSLLYVVLASLLLPGRSVFINRERANNVLQRIRRANSFFEEIKKGNLERECVEE
ICSFEEAREVFEDNEKTTEFWNKYEDGDQCESSPCQNQGECRDGLGSYTCTCTEGFEGKN
CELFVRKLCSLDNGDCDQFCREEQNSVVCSCAKGYFLGNDGKSCLSTAPFPCGKTNKGRA
KRSVALNTSNSEPDPEDLMPDADILYPTESPSELLNLNKTEPEANSDDVIRIVGGQECKR
GECPWQALLFSDEETDGFCGGTILNEFYILTAAHCLHQAKRFKVRVGDLNTEQEDGGEMV
HEVDMIIKHNKFQRDTYDFDIAMLRLKTPITFRENVAPACLPQKDWAEATLMTQKTGIVS
GFGRTHEKGRQSKVLKMMEVPYVDRNTCRLSTSFSITQNMFCAGYDAKQEDACQGDSGGP
HVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKARVGPTSETPRLTHP
PY
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| BDBM387050 |
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| n/a |
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| Name | BDBM387050 |
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| Synonyms: | 1-(4-Methoxyphenyl)-6-(2′-oxo-[1,1′-bipiperidin]-4-yl)-3-(trifluoromethyl)-5,6-dihydro-1H-pyrazolo[3,4-c]pyridin-7(4H)-one | US9938272, Example 2 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H28F3N5O3 |
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| Mol. Mass. | 491.506 |
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| SMILES | COc1ccc(cc1)-n1nc(c2CCN(C3CCN(CC3)N3CCCCC3=O)C(=O)c12)C(F)(F)F |
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| Structure | 
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