Reaction Details | |||
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Target | Vitamin D3 receptor | ||
Ligand | BDBM263383 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Dopamine D3 Receptor Binding Test | ||
Ki | 0.100±n/a nM | ||
Citation | Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Benzoisothiazole compounds and methods of treating schizophrenia US Patent US9550741 Publication Date 1/24/2017 | ||
More Info.: | Get all data from this article, Assay Method | ||
Vitamin D3 receptor | |||
Name: | Vitamin D3 receptor | ||
Synonyms: | 1,25-dihydroxyvitamin D3 receptor | NR1I1 | Nuclear receptor subfamily 1 group I member 1 | Retinoic acid receptor RXR-alpha/Vitamin D3 receptor | VDR | VDR_HUMAN | ||
Type: | Protein | ||
Mol. Mass.: | 48288.72 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P11473 | ||
Residue: | 427 | ||
Sequence: |
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BDBM263383 | |||
n/a | |||
Name | BDBM263383 | ||
Synonyms: | US9550741, I-17 | ||
Type | Small organic molecule | ||
Emp. Form. | C25H32N4OS2 | ||
Mol. Mass. | 468.678 | ||
SMILES | O=C(Cc1cccs1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1 |r,wU:9.9,wD:12.13,(-6.35,1.05,;-6.35,2.59,;-7.69,3.36,;-9.02,2.59,;-9.5,4.05,;-11.04,4.05,;-11.51,2.59,;-10.27,1.68,;-5.02,3.36,;-3.69,2.59,;-2.35,3.36,;-1.02,2.59,;-1.02,1.05,;.32,.28,;1.65,1.05,;2.98,.28,;2.98,-1.26,;4.32,-2.03,;5.65,-1.26,;5.65,.28,;4.32,1.05,;6.98,-2.03,;6.98,-3.57,;8.45,-4.05,;9.35,-2.8,;10.89,-2.64,;11.51,-1.24,;10.61,.01,;9.08,-.15,;8.45,-1.56,;-2.35,.28,;-3.69,1.05,)| | ||
Structure |