Reaction Details | |||
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Target | 5-hydroxytryptamine receptor 2A | ||
Ligand | BDBM263393 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | 5-HT2A Receptor Binding Test | ||
pH | 7.7±n/a | ||
Ki | 0.490±n/a nM | ||
Comments | extracted | ||
Citation | Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Benzoisothiazole compounds and methods of treating schizophrenia US Patent US9550741 Publication Date 1/24/2017 | ||
More Info.: | Get all data from this article, Assay Method | ||
5-hydroxytryptamine receptor 2A | |||
Name: | 5-hydroxytryptamine receptor 2A | ||
Synonyms: | 5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A | ||
Type: | undefined | ||
Mol. Mass.: | 52607.65 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P28223 | ||
Residue: | 471 | ||
Sequence: |
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BDBM263393 | |||
n/a | |||
Name | BDBM263393 | ||
Synonyms: | US9550741, II-3 | ||
Type | Small organic molecule | ||
Emp. Form. | C23H30N4O3S2 | ||
Mol. Mass. | 474.639 | ||
SMILES | O=S(=O)(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1ccco1 |r,wU:4.3,wD:7.7,(-7.08,.38,;-7.08,1.92,;-7.08,3.46,;-5.75,2.69,;-4.41,1.92,;-3.08,2.7,;-1.75,1.92,;-1.75,.38,;-.41,-.39,;.92,.38,;2.26,-.39,;2.26,-1.93,;3.59,-2.7,;4.92,-1.93,;4.92,-.39,;3.59,.38,;6.26,-2.7,;6.26,-4.24,;7.72,-4.71,;8.63,-3.47,;10.16,-3.3,;10.78,-1.9,;9.88,-.65,;8.35,-.81,;7.72,-2.22,;-3.08,-.39,;-4.41,.38,;-8.41,2.69,;-8.41,4.23,;-9.88,4.71,;-10.78,3.46,;-9.88,2.22,)| | ||
Structure |