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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Vitamin D3 receptor | ||
| Ligand | BDBM263419 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Dopamine D3 Receptor Binding Test | ||
| Ki | 0.100±n/a nM | ||
| Citation |  Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Benzoisothiazole compounds and methods of treating schizophrenia US Patent US9550741 Publication Date 1/24/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Vitamin D3 receptor | |||
| Name: | Vitamin D3 receptor | ||
| Synonyms: | 1,25-dihydroxyvitamin D3 receptor | NR1I1 | Nuclear receptor subfamily 1 group I member 1 | Retinoic acid receptor RXR-alpha/Vitamin D3 receptor | VDR | VDR_HUMAN | ||
| Type: | Protein | ||
| Mol. Mass.: | 48288.72 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P11473 | ||
| Residue: | 427 | ||
| Sequence: |
| ||
| BDBM263419 | |||
| n/a | |||
| Name | BDBM263419 | ||
| Synonyms: | US9550741, III-1 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H30N4O2S | ||
| Mol. Mass. | 402.554 | ||
| SMILES | COC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1 |r,wU:5.4,wD:8.8,(-10.27,2.93,;-8.93,3.7,;-7.6,2.93,;-7.6,1.39,;-6.26,3.7,;-4.93,2.93,;-3.6,3.7,;-2.26,2.93,;-2.26,1.39,;-.93,.62,;.4,1.39,;1.74,.62,;1.74,-.92,;3.07,-1.69,;4.4,-.92,;4.4,.62,;3.07,1.39,;5.74,-1.69,;5.74,-3.23,;7.2,-3.7,;8.11,-2.46,;9.64,-2.3,;10.27,-.89,;9.36,.36,;7.83,.2,;7.2,-1.21,;-3.6,.62,;-4.93,1.39,)| | ||
| Structure | 
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