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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | D(2) dopamine receptor | ||
| Ligand | BDBM263449 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Receptor Binding Test | ||
| pH | 7.5±n/a | ||
| Ki | 0.780±n/a nM | ||
| Comments | extracted | ||
| Citation |  Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Benzoisothiazole compounds and methods of treating schizophrenia US Patent US9550741 Publication Date 1/24/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| D(2) dopamine receptor | |||
| Name: | D(2) dopamine receptor | ||
| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 | ||
| Type: | Cell-surface receptors | ||
| Mol. Mass.: | 50647.10 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P14416 | ||
| Residue: | 443 | ||
| Sequence: |
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| BDBM263449 | |||
| n/a | |||
| Name | BDBM263449 | ||
| Synonyms: | US9550741, RGH-188 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H32Cl2N4O | ||
| Mol. Mass. | 427.411 | ||
| SMILES | CN(C)C(=O)NC1CCC(CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1 |(,-4.62,;1.33,-5.39,;2.67,-4.62,;1.33,-6.93,;,-7.7,;2.67,-7.7,;2.67,-9.24,;4,-10.01,;4,-11.55,;2.67,-12.32,;2.67,-13.86,;4,-14.63,;4,-16.17,;5.33,-16.94,;5.33,-18.48,;4,-19.25,;2.67,-18.48,;2.67,-16.94,;4,-20.79,;2.67,-21.56,;2.67,-23.1,;4,-23.87,;5.33,-23.1,;6.67,-23.87,;5.33,-21.56,;6.67,-20.79,;1.33,-11.55,;1.33,-10.01,)| | ||
| Structure | 
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