| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 15 [19-324] |
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| Ligand | BDBM10881 |
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| Substrate/Competitor | BDBM10856 |
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| Meas. Tech. | CA Inhibition Assay |
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| Ki | 65±n/a nM |
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| Citation |  Hilvo, M; Salzano, AM; Innocenti, A; Kulomaa, MS; Scozzafava, A; Scaloni, A; Parkkila, S; Supuran, CT Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV. J Med Chem52:646-54 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Carbonic anhydrase 15 [19-324] |
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| Name: | Carbonic anhydrase 15 [19-324] |
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| Synonyms: | CA-XV | CAH15_MOUSE | Ca15 | Car15 | Carbonate dehydratase XV | Carbonic Anhydrase XV |
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| Type: | Enzyme |
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| Mol. Mass.: | 33409.51 |
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| Organism: | Mus musculus (mouse) |
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| Description: | Mouse cloned isozyme. |
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| Residue: | 306 |
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| Sequence: | VDSSGTWCYDSQDPKCGPAHWKELAPACGGPTQSPINIDLRLVQRDYTLKPFIFQGYDSA
PQDPWVLENDGHTVLLRVNSCQQNCPAIRGAGLPSPEYRLLQLHFHWGSPGHQGSEHSLD
EKHGSMEMHMVHMNTKYQSMEDARSQPDGFAILAVLLVEEDRDNTNFSAIVSGLKNLSSP
GVAVNLTSTFALASLLPSALRLLRYYRYSGSLTTPGCEPAVLWTVFENTVPIGHAQVVQF
QAVLQTGPPGLHPRPLTSNFRPQQPLGGRRISASPEASVRSSVSTLPCLHLALVGLGVGL
RLWQGP
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| BDBM10881 |
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| BDBM10856 |
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| Name | BDBM10881 |
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| Synonyms: | CHEMBL288100 | MZA3 | Methazolamide | Methazolamide (MZA) | Methazolamide, MZA | N-[(2Z)-3-methyl-5-sulfamoyl-2,3-dihydro-1,3,4-thiadiazol-2-ylidene]acetamide | Sulfonamide, 2 | cid_4100 | sulfonamide 2 |
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| Type | Small organic molecule |
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| Emp. Form. | C5H8N4O3S2 |
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| Mol. Mass. | 236.272 |
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| SMILES | CC(=O)N=c1sc(nn1C)S(N)(=O)=O |w:3.2| |
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| Structure | 
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