| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM29098 |
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| Substrate/Competitor | BDBM21278 |
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| Meas. Tech. | CB Receptor Radioligand Binding Assay (Ki) |
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| pH | 7.2±n/a |
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| Temperature | 295.15±n/a K |
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| Comments | Not active. |
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| Citation |  Pettersson, H; Bülow, A; Ek, F; Jensen, J; Ottesen, LK; Fejzic, A; Ma, JN; Del Tredici, AL; Currier, EA; Gardell, LR; Tabatabaei, A; Craig, D; McFarland, K; Ott, TR; Piu, F; Burstein, ES; Olsson, R Synthesis and evaluation of dibenzothiazepines: a novel class of selective cannabinoid-1 receptor inverse agonists. J Med Chem52:1975-82 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM29098 |
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| BDBM21278 |
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| Name | BDBM29098 |
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| Synonyms: | dibenzothiazepine, 12e |
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| Type | Small organic molecule |
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| Emp. Form. | C24H21ClN2OS |
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| Mol. Mass. | 420.954 |
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| SMILES | CCCCNC(=O)c1ccc2Sc3ccccc3C(=Nc2c1)c1ccc(Cl)cc1 |c:19| |
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| Structure | 
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