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Reaction Details
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TargetRetinoic acid receptor beta [200-419]
LigandBDBM31887
Substrate/CompetitorBDBM31883
Meas. Tech.Retinoid Competition Binding Assay
pH7.9±n/a
Temperature277.15±n/a K
Kd 3.5±n/a nM
Citation Klaholz, BPMitschler, AMoras, D Structural basis for isotype selectivity of the human retinoic acid nuclear receptor. J Mol Biol302:155-70 (2000) [PubMed]  Article
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Retinoic acid receptor beta [200-419]
Name:Retinoic acid receptor beta [200-419]
Synonyms:HAP | NR1B2 | Nuclear receptor subfamily 1 group B member 2 | RAR-beta | RAR-epsilon | RARB | RARB_HUMAN | Retinoic Acid Receptor, beta
Type:Ligand-binding domain
Mol. Mass.:24708.23
Organism:Homo sapiens (Human)
Description:P10826[200-419]
Residue:220
Sequence:
PSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQIT
LLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPL
EMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILM
KITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEG
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  Blast E-value cutoff:
BDBM31887
BDBM31883
NameBDBM31887
Synonyms:BMS181156 | Ch 80
TypeSmall organic molecule
Emp. Form.C24H26O3
Mol. Mass.362.4614
SMILESCC1(C)CCC(C)(C)c2cc(ccc12)C(=O)\C=C\c1ccc(cc1)C(O)=O
Structure
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