| Reaction Details |
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 | Report a problem with these data |
| Target | Baculoviral IAP repeat-containing protein 2 [269-336] |
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| Ligand | BDBM32578 |
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| Substrate/Competitor | BDBM17342 |
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| Meas. Tech. | Fluorescence Polarization Affinity Measurements |
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| pH | 7.2±n/a |
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| Temperature | 295.15±n/a K |
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| Ki | 10±n/a nM |
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| Citation |  Ndubaku, C; Varfolomeev, E; Wang, L; Zobel, K; Lau, K; Elliott, LO; Maurer, B; Fedorova, AV; Dynek, JN; Koehler, M; Hymowitz, SG; Tsui, V; Deshayes, K; Fairbrother, WJ; Flygare, JA; Vucic, D Antagonism of c-IAP and XIAP proteins is required for efficient induction of cell death by small-molecule IAP antagonists. ACS Chem Biol4:557-66 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Inhibition_Run data, Solution Info, Assay Method |
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| Baculoviral IAP repeat-containing protein 2 [269-336] |
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| Name: | Baculoviral IAP repeat-containing protein 2 [269-336] |
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| Synonyms: | API1 | BIRC2 | BIRC2_HUMAN | Baculoviral IAP repeat-containing protein 2 | IAP homolog B | Inhibitor of apoptosis protein 2 | MIHB | RNF48 | cIAP-1 BIR3 |
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| Type: | BIR3 domain |
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| Mol. Mass.: | 7949.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13490[269-336] |
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| Residue: | 68 |
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| Sequence: | HAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVEHAK
WFPRCEFL
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| BDBM32578 |
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| BDBM17342 |
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| Name | BDBM32578 |
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| Synonyms: | CS-1 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H40N6O3 |
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| Mol. Mass. | 508.6556 |
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| SMILES | CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N1CC[C@H](C)[C@H]1C(=O)Nc1cc(C)nn1-c1ccccc1 |r| |
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| Structure | 
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