| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Baculoviral IAP repeat-containing protein 3 [255-322] |
|---|
| Ligand | BDBM32578 |
|---|
| Substrate/Competitor | BDBM17342 |
|---|
| Meas. Tech. | Fluorescence Polarization Affinity Measurements |
|---|
| pH | 7.2±n/a |
|---|
| Temperature | 295.15±n/a K |
|---|
| Ki | 52±n/a nM |
|---|
| Citation |  Ndubaku, C; Varfolomeev, E; Wang, L; Zobel, K; Lau, K; Elliott, LO; Maurer, B; Fedorova, AV; Dynek, JN; Koehler, M; Hymowitz, SG; Tsui, V; Deshayes, K; Fairbrother, WJ; Flygare, JA; Vucic, D Antagonism of c-IAP and XIAP proteins is required for efficient induction of cell death by small-molecule IAP antagonists. ACS Chem Biol4:557-66 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Inhibition_Run data, Solution Info, Assay Method |
|---|
| |
| Baculoviral IAP repeat-containing protein 3 [255-322] |
|---|
| Name: | Baculoviral IAP repeat-containing protein 3 [255-322] |
|---|
| Synonyms: | API2 | Apoptosis inhibitor 2 | BIRC3 | BIRC3_HUMAN | Baculoviral IAP repeat-containing protein 3 | Inhibitor of apoptosis protein 1 | MIHC | RNF49 | cIAP-2 BIR3 |
|---|
| Type: | BIR3 domain |
|---|
| Mol. Mass.: | 7852.71 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q13489[255-322] |
|---|
| Residue: | 68 |
|---|
| Sequence: | HAARFKTFFNWPSSVLVNPEQLASAGFYYVGNSDDVKCFCCDGGLRCWESGDDPWVQHAK
WFPRCEYL
|
|
|
|---|
| BDBM32578 |
|---|
| BDBM17342 |
|---|
| Name | BDBM32578 |
|---|
| Synonyms: | CS-1 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C28H40N6O3 |
|---|
| Mol. Mass. | 508.6556 |
|---|
| SMILES | CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N1CC[C@H](C)[C@H]1C(=O)Nc1cc(C)nn1-c1ccccc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
