| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 7 |
|---|
| Ligand | BDBM33281 |
|---|
| Substrate/Competitor | BDBM10856 |
|---|
| Meas. Tech. | CA Inhibition Assay |
|---|
| Ki | 79.6±n/a nM |
|---|
| Citation |  Vitale, RM; Alterio, V; Innocenti, A; Winum, JY; Monti, SM; De Simone, G; Supuran, CT Carbonic anhydrase inhibitors. Comparison of aliphatic sulfamate/bis-sulfamate adducts with isozymes II and IX as a platform for designing tight-binding, more isoform-selective inhibitors. J Med Chem52:5990-8 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Carbonic anhydrase 7 |
|---|
| Name: | Carbonic anhydrase 7 |
|---|
| Synonyms: | CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 29664.11 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Human cloned isozyme. |
|---|
| Residue: | 264 |
|---|
| Sequence: | MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
|
|
|
|---|
| BDBM33281 |
|---|
| BDBM10856 |
|---|
| Name | BDBM33281 |
|---|
| Synonyms: | CHEMBL182455 | bis-sulfamate, 3 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C8H20N2O6S2 |
|---|
| Mol. Mass. | 304.384 |
|---|
| SMILES | NS(=O)(=O)OCCCCCCCCOS(N)(=O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
