| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase |
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| Ligand | BDBM10871 |
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| Substrate/Competitor | BDBM10856 |
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| Meas. Tech. | CA Inhibition Assay |
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| pH | 8.3±n/a |
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| Temperature | 293.15±n/a K |
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| Ki | 1310±n/a nM |
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| Citation |  Innocenti, A; Hall, RA; Schlicker, C; Scozzafava, A; Steegborn, C; Mühlschlegel, FA; Supuran, CT Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal beta-carbonic anhydrase from Candida albicans with sulfonamides. Bioorg Med Chem17:4503-9 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Carbonic anhydrase |
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| Name: | Carbonic anhydrase |
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| Synonyms: | CAN_CANAL | NCE103 | beta-Carbonic Anhydrase |
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| Type: | Enzyme |
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| Mol. Mass.: | 31587.59 |
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| Organism: | Candida albicans (Yeast) |
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| Description: | n/a |
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| Residue: | 281 |
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| Sequence: | MGRENILKYQLEHDHESDLVTEKDQSLLLDNNNNLNGMNNTIKTHPVRVSSGNHNNFPFT
LSSESTLQDFLNNNKFFVDSIKHNHGNQIFDLNGQGQSPHTLWIGCSDSRAGDQCLATLP
GEIFVHRNIANIVNANDISSQGVIQFAIDVLKVKKIIVCGHTDCGGIWASLSKKKIGGVL
DLWLNPVRHIRAANLKLLEEYNQDPKLKAKKLAELNVISSVTALKRHPSASVALKKNEIE
VWGMLYDVATGYLSQVEIPQDEFEDLFHVHDEHDEEEYNPH
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| BDBM10871 |
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| BDBM10856 |
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| Name | BDBM10871 |
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| Synonyms: | 4-amino-N-[(4-sulfamoylphenyl)methyl]benzene-1-sulfonamide | CHEMBL266026 | aromatic/heteroaromatic sulfonamide 16 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H15N3O4S2 |
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| Mol. Mass. | 341.406 |
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| SMILES | Nc1ccc(cc1)S(=O)(=O)NCc1ccc(cc1)S(N)(=O)=O |
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| Structure | 
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