| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 2 |
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| Ligand | BDBM35997 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SPR biosensor assay Biacore T100 |
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| pH | 7.4±n/a |
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| Temperature | 298.15±n/a K |
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| Kd | 38900±n/a nM |
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| KOFF | 49900 s-1 |
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| KON | 1.94 M-1s-1 |
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| Citation |  Navratilova, I; Hopkins, AL Fragment Screening by Surface Plasmon Resonance ACS Med Chem Lett1:44-8 (2010) |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Carbonic anhydrase 2 |
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| Name: | Carbonic anhydrase 2 |
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| Synonyms: | CA2 | CAH2_BOVIN | Carbonic anhydrase | Carbonic anhydrase 2 | Carbonic anhydrase II | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 29115.93 |
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| Organism: | Bos taurus |
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| Description: | n/a |
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| Residue: | 260 |
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| Sequence: | MSHHWGYGKHNGPEHWHKDFPIANGERQSPVDIDTKAVVQDPALKPLALVYGEATSRRMV
NNGHSFNVEYDDSQDKAVLKDGPLTGTYRLVQFHFHWGSSDDQGSEHTVDRKKYAAELHL
VHWNTKYGDFGTAAQQPDGLAVVGVFLKVGDANPALQKVLDALDSIKTKGKSTDFPNFDP
GSLLPNVLDYWTYPGSLTTPPLLESVTWIVLKEPISVSSQQMLKFRTLNFNAEGEPELLM
LANWRPAQPLKNRQVRGFPK
|
|
|
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| BDBM35997 |
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| n/a |
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| Name | BDBM35997 |
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| Synonyms: | 1,4-dioxo-1,2,3,4-tetrahydro-1,2,3-benzothiadiazin-1-ium-1-olate | SPR_1 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H6N2O3S |
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| Mol. Mass. | 198.199 |
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| SMILES | O=C1NNS(=O)(=O)c2ccccc12 |
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| Structure | 
|
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