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Reaction Details
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TargetCarbonic anhydrase
LigandBDBM35997
Substrate/Competitorn/a
Meas. Tech.SPR biosensor assay Biacore T100
pH7.4±n/a
Temperature298.15±n/a K
Kd 38900±n/a nM
KOFF 49900 s-1
KON 1.94 M-1s-1
Citation Navratilova IHopkins AL Fragment Screening by Surface Plasmon Resonance ACS Med Chem Lett 1:44-8 (2010)  
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Carbonic anhydrase
Name:Carbonic anhydrase
Synonyms:Carbonic anhydrase 2 | Carbonic anhydrase II | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II)
Type:Enzyme Catalytic Domain
Mol. Mass.:29115.93
Organism:Bos taurus
Description:n/a
Residue:260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIANGERQSPVDIDTKAVVQDPALKPLALVYGEATSRRMV
NNGHSFNVEYDDSQDKAVLKDGPLTGTYRLVQFHFHWGSSDDQGSEHTVDRKKYAAELHL
VHWNTKYGDFGTAAQQPDGLAVVGVFLKVGDANPALQKVLDALDSIKTKGKSTDFPNFDP
GSLLPNVLDYWTYPGSLTTPPLLESVTWIVLKEPISVSSQQMLKFRTLNFNAEGEPELLM
LANWRPAQPLKNRQVRGFPK
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  Blast E-value cutoff:
BDBM35997
n/a
NameBDBM35997
Synonyms:1,4-dioxo-1,2,3,4-tetrahydro-1,2,3-benzothiadiazin-1-ium-1-olate | SPR_1
TypeSmall organic molecule
Emp. Form.C7H6N2O3S
Mol. Mass.198.199
SMILESO=C1NNS(=O)(=O)c2ccccc12
Structure
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