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Reaction Details
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TargetCarbonic anhydrase
LigandBDBM10888
Substrate/Competitorn/a
Meas. Tech.SPR biosensor assay Biacore T100
pH7.4±n/a
Temperature298.15±n/a K
Kd 4260±n/a nM
KOFF 143000 s-1
KON 0.611 M-1s-1
Citation Navratilova IHopkins AL Fragment Screening by Surface Plasmon Resonance ACS Med Chem Lett 1:44-8 (2010)  
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Carbonic anhydrase
Name:Carbonic anhydrase
Synonyms:Carbonic anhydrase 2 | Carbonic anhydrase II | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II)
Type:Enzyme Catalytic Domain
Mol. Mass.:29115.93
Organism:Bos taurus
Description:n/a
Residue:260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIANGERQSPVDIDTKAVVQDPALKPLALVYGEATSRRMV
NNGHSFNVEYDDSQDKAVLKDGPLTGTYRLVQFHFHWGSSDDQGSEHTVDRKKYAAELHL
VHWNTKYGDFGTAAQQPDGLAVVGVFLKVGDANPALQKVLDALDSIKTKGKSTDFPNFDP
GSLLPNVLDYWTYPGSLTTPPLLESVTWIVLKEPISVSSQQMLKFRTLNFNAEGEPELLM
LANWRPAQPLKNRQVRGFPK
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  Blast E-value cutoff:
BDBM10888
n/a
NameBDBM10888
Synonyms:1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 | SPR_2 | US10172837, Zonisamide | Zonisamide | Zonisamide (ZNA) | Zonisamide (ZNS) | Zonisamide, 1 | Zonisamide, ZNS
TypeSmall organic molecule
Emp. Form.C8H8N2O3S
Mol. Mass.212.226
SMILESNS(=O)(=O)Cc1noc2ccccc12
Structure
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