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Reaction Details
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TargetCarbonic anhydrase
LigandBDBM36004
Substrate/Competitorn/a
Meas. Tech.SPR biosensor assay Biacore T100
pH7.4±n/a
Temperature298.15±n/a K
Kd 394±n/a nM
KOFF 272000 s-1
KON 0.1073 M-1s-1
Citation Navratilova IHopkins AL Fragment Screening by Surface Plasmon Resonance ACS Med Chem Lett 1:44-8 (2010)  
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Carbonic anhydrase
Name:Carbonic anhydrase
Synonyms:Carbonic anhydrase 2 | Carbonic anhydrase II | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II)
Type:Enzyme Catalytic Domain
Mol. Mass.:29115.93
Organism:Bos taurus
Description:n/a
Residue:260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIANGERQSPVDIDTKAVVQDPALKPLALVYGEATSRRMV
NNGHSFNVEYDDSQDKAVLKDGPLTGTYRLVQFHFHWGSSDDQGSEHTVDRKKYAAELHL
VHWNTKYGDFGTAAQQPDGLAVVGVFLKVGDANPALQKVLDALDSIKTKGKSTDFPNFDP
GSLLPNVLDYWTYPGSLTTPPLLESVTWIVLKEPISVSSQQMLKFRTLNFNAEGEPELLM
LANWRPAQPLKNRQVRGFPK
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BDBM36004
n/a
NameBDBM36004
Synonyms:2,4-difluorobenzene-1-sulfonamide | SPR_8
TypeSmall organic molecule
Emp. Form.C6H5F2NO2S
Mol. Mass.193.171
SMILESNS(=O)(=O)c1ccc(F)cc1F
Structure
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