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TargetCathepsin B
LigandBDBM36331
Substrate/CompetitorBDBM36388
Meas. Tech.Assay name: Protease Inhibition Assay
pH5.5±0
Temperature310.15±0 K
IC50 7.3±n/a nM
Citation Kato, DBoatright, KMBerger, ABNazif, TBlum, GRyan, CChehade, KASalvesen, GSBogyo, M Activity-based probes that target diverse cysteine protease families. Nat Chem Biol1:33-8 (2005) [PubMed]  Article
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Cathepsin B
Name:Cathepsin B
Synonyms:CATB_RAT | Ctsb
Type:Protein
Mol. Mass.:37463.53
Organism:Rattus norvegicus
Description:P00787
Residue:339
Sequence:
MWWSLIPLSCLLALTSAHDKPSSHPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCG
TVLGGPNLPERVGFSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDR
ICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCL
PYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIM
AEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSW
NVDWGDNGFFKILRGENHCGIESEIVAGIPRTQQYWGRF
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BDBM36331
BDBM36388
NameBDBM36331
Synonyms:Ac-YFR-AMOK 10b
TypeSmall organic molecule
Emp. Form.C36H44N6O7
Mol. Mass.672.7706
SMILES[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#6]-[#8]-[#6](=O)-c1c(-[#6])cccc1-[#6]
Structure
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