| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin Z |
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| Ligand | BDBM36331 |
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| Substrate/Competitor | BDBM36388 |
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| Meas. Tech. | Assay name: Protease Inhibition Assay |
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| pH | 5.5±0 |
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| Temperature | 310.15±0 K |
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| IC50 | 4.7e+3±n/a nM |
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| Citation |  Kato, D; Boatright, KM; Berger, AB; Nazif, T; Blum, G; Ryan, C; Chehade, KA; Salvesen, GS; Bogyo, M Activity-based probes that target diverse cysteine protease families. Nat Chem Biol1:33-8 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Cathepsin Z |
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| Name: | Cathepsin Z |
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| Synonyms: | CATZ_RAT | Ctsy | Ctsz |
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| Type: | Protein |
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| Mol. Mass.: | 34197.61 |
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| Organism: | Rattus norvegicus |
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| Description: | Q9R1T3 |
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| Residue: | 306 |
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| Sequence: | MASSGSVQQLRLVLLMLLLAGAARASLYFRPGQTCYRPLHRDHLALLGRRTYPRPHEYLS
PADLPKNWDWRNVNGVNYASVTRNQHIPQYCGSCWAHGSTSALADRINIKRKGAWPSTLL
SVQNVIDCGNAGSCEGGNDLPVWEYAHKHGIPDETCNNYQAKDQECDKFNQCGTCTEFKE
CHTIQNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERMSNYTGGIYTEYQNQAI
INHIISVAGWGVSNDGIEYWIVRNSWGEPWGERGWMRIVTSTYKGGTGSSYNLAIEEACT
FGDPIV
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| BDBM36331 |
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| BDBM36388 |
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| Name | BDBM36331 |
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| Synonyms: | Ac-YFR-AMOK 10b |
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| Type | Small organic molecule |
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| Emp. Form. | C36H44N6O7 |
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| Mol. Mass. | 672.7706 |
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| SMILES | [#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#6]-[#8]-[#6](=O)-c1c(-[#6])cccc1-[#6] |
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| Structure | 
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