| Reaction Details |
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 | Report a problem with these data |
| Target | Pro-cathepsin H |
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| Ligand | BDBM36325 |
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| Substrate/Competitor | BDBM36388 |
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| Meas. Tech. | Assay name: Protease Inhibition Assay |
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| pH | 5.5±0 |
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| Temperature | 310.15±0 K |
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| IC50 | 6.6e+3±n/a nM |
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| Citation |  Kato, D; Boatright, KM; Berger, AB; Nazif, T; Blum, G; Ryan, C; Chehade, KA; Salvesen, GS; Bogyo, M Activity-based probes that target diverse cysteine protease families. Nat Chem Biol1:33-8 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Pro-cathepsin H |
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| Name: | Pro-cathepsin H |
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| Synonyms: | CATH_RAT | Cathepsin H | Ctsh |
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| Type: | PROTEIN |
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| Mol. Mass.: | 37114.31 |
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| Organism: | Rattus norvegicus |
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| Description: | P00786 |
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| Residue: | 333 |
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| Sequence: | MWTALPLLCAGAWLLSAGATAELTVNAIEKFHFTSWMKQHQKTYSSREYSHRLQVFANNW
RKIQAHNQRNHTFKMGLNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPSSMDW
RKKGNVVSPVKNQGACGSCWTFSTTGALESAVAIASGKMMTLAEQQLVDCAQNFNNHGCQ
GGLPSQAFEYILYNKGIMGEDSYPYIGKNGQCKFNPEKAVAFVKNVVNITLNDEAAMVEA
VALYNPVSFAFEVTEDFMMYKSGVYSSNSCHKTPDKVNHAVLAVGYGEQNGLLYWIVKNS
WGSNWGNNGYFLIERGKNMCGLAACASYPIPQV
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| BDBM36325 |
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| BDBM36388 |
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| Name | BDBM36325 |
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| Synonyms: | Cathepsin Inhibitor III |
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| Type | Small organic molecule |
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| Emp. Form. | C27H27N3O7 |
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| Mol. Mass. | 505.5192 |
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| SMILES | COc1ccc(cc1)C(=O)ONC(=O)CNC(=O)C(Cc1ccccc1)NC(=O)OCc1ccccc1 |
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| Structure | 
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