| Reaction Details |
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 | Report a problem with these data |
| Target | Kaposi's sarcoma-associated herpesvirus cyclin homolog |
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| Ligand | BDBM36460 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | KSHV Pr Inhibition Assay |
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| pH | 8±0 |
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| Temperature | 303.15±0 K |
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| IC50 | 3.1e+3± 2e+2 nM |
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| Citation |  Shahian, T; Lee, GM; Lazic, A; Arnold, LA; Velusamy, P; Roels, CM; Guy, RK; Craik, CS Inhibition of a viral enzyme by a small-molecule dimer disruptor. Nat Chem Biol5:640-6 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Kaposi's sarcoma-associated herpesvirus cyclin homolog |
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| Name: | Kaposi's sarcoma-associated herpesvirus cyclin homolog |
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| Synonyms: | Kaposi's sarcoma-associated herpesvirus (KSHV) |
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| Type: | Enzyme |
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| Mol. Mass.: | 28080.00 |
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| Organism: | Human herpesvirus 8 (HHV-8) (Kaposi's sarcoma-associated herpesvirus) |
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| Description: | Q98147 |
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| Residue: | 257 |
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| Sequence: | MATANNPPSGLLDPTLCEDRIFYNILEIEPRFLTSDSVFGTFQQSLTSHMRKLLGTWMFS
VCQEYNLEPNVVALALNLLDRLLLIKQVSKEHFQKTGSACLLVASKLRSLTPISTSSLCY
AAADSFSRQELIDQEKELLEKLAWRTEAVLATDVTSFLLLKLVGGSQHLDFWHHEVNTLI
TKALVDPKTGSLPASIISAAGCALLVPANVIPQDTHSGGVVPQLASILGCDVSVLQAAVE
QILTSVSDFDLRILDSY
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| BDBM36460 |
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| n/a |
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| Name | BDBM36460 |
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| Synonyms: | 3-Benzyl-4-(6-(cyclohexylmethyl)picolinamido)benzoic acid, 2 | CID42628632 | DD2 |
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| Type | Small organic moelcule |
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| Emp. Form. | C27H28N2O3 |
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| Mol. Mass. | 428.5228 |
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| SMILES | OC(=O)c1ccc(NC(=O)c2cccc(CC3CCCCC3)n2)c(Cc2ccccc2)c1 |
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| Structure | 
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