| Reaction Details |
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 | Report a problem with these data |
| Target | HIV-1 protease |
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| Ligand | BDBM36652 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Protease Inhibtion Assay |
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| pH | 5.5±0 |
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| Ki | 0.34±0.0 nM |
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| Citation |  Rodgers, JD; Lam, PY; Johnson, BL; Wang, H; Li, R; Ru, Y; Ko, SS; Seitz, SP; Trainor, GL; Anderson, PS; Klabe, RM; Bacheler, LT; Cordova, B; Garber, S; Reid, C; Wright, MR; Chang, CH; Erickson-Viitanen, S Design and selection of DMP 850 and DMP 851: the next generation of cyclic urea HIV protease inhibitors. Chem Biol5:597-608 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| HIV-1 protease |
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| Name: | HIV-1 protease |
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| Synonyms: | HIV-1 protease wild type |
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| Type: | Protein |
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| Mol. Mass.: | 10757.68 |
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| Organism: | Human immunodeficiency virus |
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| Description: | O90785 |
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| Residue: | 99 |
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| Sequence: | PQITLWQRPLVTVKIGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYE
QVLIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF
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| BDBM36652 |
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| n/a |
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| Name | BDBM36652 |
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| Synonyms: | 3-alkylaminoindazole cyclic urea, (c-PrCH2-) |
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| Type | Small organic molecule |
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| Emp. Form. | C41H44N8O3 |
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| Mol. Mass. | 696.8399 |
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| SMILES | O[C@@H]1[C@@H](O)[C@@H](Cc2ccccc2)N(Cc2ccc3[nH]nc(NC4CC4)c3c2)C(=O)N(Cc2ccc3[nH]nc(NC4CC4)c3c2)[C@@H]1Cc1ccccc1 |r| |
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| Structure | 
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