| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Protein-tyrosine kinase 6 |
|---|
| Ligand | BDBM21 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Kinase Inhibitor Selectivity Profiling Assay |
|---|
| Kd | 160±n/a nM |
|---|
| Citation |  PubChem, PC Kinase Inhibitor Selectivity Profiling Assay PubChem Bioassay(2008)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Protein-tyrosine kinase 6 |
|---|
| Name: | Protein-tyrosine kinase 6 |
|---|
| Synonyms: | BRK | Breast tumor kinase | KH domain-containing, RNA-binding, signal transduction-associated protein 1 | PTK6 | PTK6_HUMAN | Protein-tyrosine kinase 6 (BRK) | Tyrosine Kinase BRK | Tyrosine-protein kinase 6 | Tyrosine-protein kinase BRK |
|---|
| Type: | Tyrosine-protein kinase |
|---|
| Mol. Mass.: | 51839.11 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 451 |
|---|
| Sequence: | MVSRDQAHLGPKYVGLWDFKSRTDEELSFRAGDVFHVARKEEQWWWATLLDEAGGAVAQG
YVPHNYLAERETVESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRD
TQAVRHYKIWRRAGGRLHLNEAVSFLSLPELVNYHRAQSLSHGLRLAAPCRKHEPEPLPH
WDDWERPREEFTLCRKLGSGYFGEVFEGLWKDRVQVAIKVISRDNLLHQQMLQSEIQAMK
KLRHKHILALYAVVSVGDPVYIITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGM
CYLESQNYIHRDLAARNILVGENTLCKVGDFGLARLIKEDVYLSHDHNIPYKWTAPEALS
RGHYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVDAGYRMPCPLECPPSVHKLM
LTCWCRDPEQRPCFKALRERLSSFTSYENPT
|
|
|
|---|
| BDBM21 |
|---|
| n/a |
|---|
| Name | BDBM21 |
|---|
| Synonyms: | CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine | VANDETANIB | ZD-6474 | ZD6474 | cid_3081361 |
|---|
| Type | n/a |
|---|
| Emp. Form. | C22H24BrFN4O2 |
|---|
| Mol. Mass. | 475.354 |
|---|
| SMILES | COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
