| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Interleukin-1 receptor-associated kinase 3 |
|---|
| Ligand | BDBM26474 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Kinase Inhibitor Selectivity Profiling Assay |
|---|
| Kd | 800000±n/a nM |
|---|
| Citation |  PubChem, PC Kinase Inhibitor Selectivity Profiling Assay PubChem Bioassay(2008)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Interleukin-1 receptor-associated kinase 3 |
|---|
| Name: | Interleukin-1 receptor-associated kinase 3 |
|---|
| Synonyms: | IL-1 receptor-associated kinase M | IRAK-3 | IRAK-M | IRAK3 | IRAK3_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 67767.98 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | EBI_101055 |
|---|
| Residue: | 596 |
|---|
| Sequence: | MAGNCGARGALSAHTLLFDLPPALLGELCAVLDSCDGALGWRGLAERLSSSWLDVRHIEK
YVDQGKSGTRELLWSWAQKNKTIGDLLQVLQEMGHRRAIHLITNYGAVLSPSEKSYQEGG
FPNILFKETANVTVDNVLIPEHNEKGILLKSSISFQNIIEGTRNFHKDFLIGEGEIFEVY
RVEIQNLTYAVKLFKQEKKMQCKKHWKRFLSELEVLLLFHHPNILELAAYFTETEKFCLI
YPYMRNGTLFDRLQCVGDTAPLPWHIRIGILIGISKAIHYLHNVQPCSVICGSISSANIL
LDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTDVYSF
GIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFC
LAGRCAATRAKLRPSMDEVLNTLESTQASLYFAEDPPTSLKSFRCPSPLFLENVPSIPVE
DDESQNNNLLPSDEGLRIDRMTQKTPFECSQSEVMFLSLDKKPESKRNEEACNMPSSSCE
ESWFPKYIVPSQDLRPYKVNIDPSSEAPGHSCRSRPVESSCSSKFSWDEYEQYKKE
|
|
|
|---|
| BDBM26474 |
|---|
| n/a |
|---|
| Name | BDBM26474 |
|---|
| Synonyms: | 5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl}amino)-2-methylbenzene-1-sulfonamide | GW-786034 | JMC514632 Compound 13 | Pazopanib | cid_10113978 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H23N7O2S |
|---|
| Mol. Mass. | 437.518 |
|---|
| SMILES | CN(c1ccc2c(C)n(C)nc2c1)c1ccnc(Nc2ccc(C)c(c2)S(N)(=O)=O)n1 |
|---|
| Structure | 
|
|---|
Search and Browse
