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Reaction Details
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TargetPantothenate synthetase
LigandBDBM37287
Substrate/Competitorn/a
Meas. Tech.Mycobacterium tuberculosis Pantothenate Synthetase Assay
IC50>100000±n/a nM
CommentsExtracted from aid = 375 and tid = 12
Citation PubChem, PC Mycobacterium tuberculosis Pantothenate Synthetase Assay PubChem Bioassay(2006)[AID]
More Info.:Get all data from this article,  Assay Method
 
Pantothenate synthetase
Name:Pantothenate synthetase
Synonyms:Chain A, Crystal Structure Of A Pantothenate Synthetase, Apo Enzyme In C2 Space Group | PANC_MYCTU | Pantothenate synthetase | panC
Type:n/a
Mol. Mass.:32675.10
Organism:Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Description:ChEMBL_102878
Residue:309
Sequence:
MTIPAFHPGELNVYSAPGDVADVSRALRLTGRRVMLVPTMGALHEGHLALVRAAKRVPGS
VVVVSIFVNPMQFGAGEDLDAYPRTPDDDLAQLRAEGVEIAFTPTTAAMYPDGLRTTVQP
GPLAAELEGGPRPTHFAGVLTVVLKLLQIVRPDRVFFGEKDYQQLVLIRQLVADFNLDVA
VVGVPTVREADGLAMSSRNRYLDPAQRAAAVALSAALTAAAHAATAGAQAALDAARAVLD
AAPGVAVDYLELRDIGLGPMPLNGSGRLLVAARLGTTRLLDNIAIEIGTFAGTDRPDGYR
AILESHWRN
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  Blast E-value cutoff:
BDBM37287
n/a
NameBDBM37287
Synonyms:MLS000087275 | N-[1-(4-methylbenzyl)-1H-pyrazol-3-yl]-5-thien-2-ylisoxazole-3-carboxamide | N-[1-(4-methylbenzyl)pyrazol-3-yl]-5-(2-thienyl)isoxazole-3-carboxamide | N-[1-[(4-methylphenyl)methyl]-3-pyrazolyl]-5-thiophen-2-yl-3-isoxazolecarboxamide | N-[1-[(4-methylphenyl)methyl]pyrazol-3-yl]-5-thiophen-2-yl-1,2-oxazole-3-carboxamide | SMR000023498 | cid_3236204
TypeSmall organic molecule
Emp. Form.C19H16N4O2S
Mol. Mass.364.421
SMILESCc1ccc(Cn2ccc(NC(=O)c3cc(on3)-c3cccs3)n2)cc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: