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Reaction Details
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TargetPantothenate synthetase
LigandBDBM37291
Substrate/Competitorn/a
Meas. Tech.Mycobacterium tuberculosis Pantothenate Synthetase Assay
IC50>100000±n/a nM
CommentsExtracted from aid = 375 and tid = 22
Citation PubChem, PC Mycobacterium tuberculosis Pantothenate Synthetase Assay PubChem Bioassay(2006)[AID]
More Info.:Get all data from this article,  Assay Method
 
Pantothenate synthetase
Name:Pantothenate synthetase
Synonyms:Chain A, Crystal Structure Of A Pantothenate Synthetase, Apo Enzyme In C2 Space Group | PANC_MYCTU | Pantothenate synthetase | panC
Type:n/a
Mol. Mass.:32675.10
Organism:Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Description:ChEMBL_102878
Residue:309
Sequence:
MTIPAFHPGELNVYSAPGDVADVSRALRLTGRRVMLVPTMGALHEGHLALVRAAKRVPGS
VVVVSIFVNPMQFGAGEDLDAYPRTPDDDLAQLRAEGVEIAFTPTTAAMYPDGLRTTVQP
GPLAAELEGGPRPTHFAGVLTVVLKLLQIVRPDRVFFGEKDYQQLVLIRQLVADFNLDVA
VVGVPTVREADGLAMSSRNRYLDPAQRAAAVALSAALTAAAHAATAGAQAALDAARAVLD
AAPGVAVDYLELRDIGLGPMPLNGSGRLLVAARLGTTRLLDNIAIEIGTFAGTDRPDGYR
AILESHWRN
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  Blast E-value cutoff:
BDBM37291
n/a
NameBDBM37291
Synonyms:MLS000087136 | N-[1-(4-chlorobenzyl)-5-methyl-1H-pyrazol-3-yl]-5-(3,4-dimethoxyphenyl)isoxazole-3-carboxamide | N-[1-(4-chlorobenzyl)-5-methyl-pyrazol-3-yl]-5-(3,4-dimethoxyphenyl)isoxazole-3-carboxamide | N-[1-[(4-chlorophenyl)methyl]-5-methyl-3-pyrazolyl]-5-(3,4-dimethoxyphenyl)-3-isoxazolecarboxamide | N-[1-[(4-chlorophenyl)methyl]-5-methyl-pyrazol-3-yl]-5-(3,4-dimethoxyphenyl)-1,2-oxazole-3-carboxamide | N-[1-[(4-chlorophenyl)methyl]-5-methylpyrazol-3-yl]-5-(3,4-dimethoxyphenyl)-1,2-oxazole-3-carboxamide | SMR000023359 | cid_3237184
TypeSmall organic molecule
Emp. Form.C23H21ClN4O4
Mol. Mass.452.89
SMILESCOc1ccc(cc1OC)-c1cc(no1)C(=O)Nc1cc(C)n(Cc2ccc(Cl)cc2)n1
Structure
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