| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 6 |
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| Ligand | BDBM35364 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In vitro MKP-3 Phosphatase Dose Response Confirmation and Secondary Selectivity/Selectivity Assay |
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| IC50 | 41190±n/a nM |
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| Citation |  PubChem, PC In vitro MKP-3 Phosphatase Dose Response Confirmation and Secondary Selectivity/Selectivity Assay PubChem Bioassay(2006)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Dual specificity protein phosphatase 6 |
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| Name: | Dual specificity protein phosphatase 6 |
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| Synonyms: | DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42303.19 |
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| Organism: | Rattus norvegicus |
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| Description: | gi_16758752 |
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| Residue: | 381 |
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| Sequence: | MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPG
IMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLK
KLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI
ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT
PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS
VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQ
QLYFTAPSNQNVYQVDSLQST
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| BDBM35364 |
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| n/a |
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| Name | BDBM35364 |
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| Synonyms: | MLS000079944 | SMR000040944 | cid_659878 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H21N5O3 |
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| Mol. Mass. | 451.4766 |
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| SMILES | COc1ccc(Cn2c(C)nc3n(Cc4ccco4)c4nc5ccccc5nc4c3c2=O)cc1 |
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| Structure | 
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