| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mevalonate kinase |
|---|
| Ligand | BDBM38606 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response |
|---|
| IC50 | 25018.3±n/a nM |
|---|
| Citation |  PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response PubChem Bioassay(2007)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Mevalonate kinase |
|---|
| Name: | Mevalonate kinase |
|---|
| Synonyms: | n/a |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 31420.64 |
|---|
| Organism: | Streptococcus pneumoniae D39 |
|---|
| Description: | A0A0H2ZQX9 |
|---|
| Residue: | 292 |
|---|
| Sequence: | MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVPAESPWRLYEEDTLSMA
VYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRAVFDYYQADLPHDVLEILV
NRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGVYGHTREAIQ
VVQNKGKDALPFLHALGELTQQAEIAISQKDAEGLGQILSQAHLHLKEIGVSSLEADSLV
ETALSHGALGAKMSGGGLGGCIIALVTNLTHAQELAERLEEKGAVQTWIESL
|
|
|
|---|
| BDBM38606 |
|---|
| n/a |
|---|
| Name | BDBM38606 |
|---|
| Synonyms: | 7-(3,5-dimethoxyanilino)-6-(2-furanylmethyl)-7H-pyrrolo[3,4-b]pyridin-5-one | 7-(3,5-dimethoxyanilino)-6-(2-furfuryl)-7H-pyrrolo[3,4-b]pyridin-5-one | 7-(3,5-dimethoxyanilino)-6-(furan-2-ylmethyl)-7H-pyrrolo[3,4-b]pyridin-5-one | 7-[(3,5-dimethoxyphenyl)amino]-6-(2-furylmethyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one | 7-[(3,5-dimethoxyphenyl)amino]-6-(furan-2-ylmethyl)-7H-pyrrolo[3,4-b]pyridin-5-one | MLS000254464 | SMR000028156 | cid_3241207 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H19N3O4 |
|---|
| Mol. Mass. | 365.3826 |
|---|
| SMILES | COc1cc(Nc2n(Cc3ccco3)c(=O)c3ccc[nH]c23)cc(OC)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
