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Reaction Details
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TargetSteroidogenic factor 1
LigandBDBM38956
Substrate/Competitorn/a
Meas. Tech.Dose-response cell-based assay for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1)
IC50 189±n/a nM
Citation PubChem, PC Dose-response cell-based assay for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1) PubChem Bioassay(2007)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Steroidogenic factor 1
Name:Steroidogenic factor 1
Synonyms:AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:Nuclear Hormone Receptor
Mol. Mass.:51643.43
Organism:Homo sapiens (Human)
Description:n/a
Residue:461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKT
QRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKL
ETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPL
AGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQV
RARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQN
CWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLA
LQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLL
LCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
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  Blast E-value cutoff:
BDBM38956
n/a
NameBDBM38956
Synonyms:2-({[2-(4-ethoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methyl}thio)-N-(2-furylmethyl)acetamide | 2-[[2-(4-ethoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methylsulfanyl]-N-(furan-2-ylmethyl)acetamide | 2-[[2-(4-ethoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methylsulfanyl]-N-(furan-2-ylmethyl)ethanamide | 2-[[2-(4-ethoxyphenyl)-5-methyl-4-oxazolyl]methylthio]-N-(2-furanylmethyl)acetamide | MLS000046849 | N-(2-furfuryl)-2-[(5-methyl-2-p-phenetyl-oxazol-4-yl)methylthio]acetamide | SMR000032860 | cid_3237327
TypeSmall organic molecule
Emp. Form.C20H22N2O4S
Mol. Mass.386.465
SMILESCCOc1ccc(cc1)-c1nc(CSCC(=O)NCc2ccco2)c(C)o1
Structure
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