| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Steroidogenic factor 1 |
|---|
| Ligand | BDBM38962 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose-response cell-based assay for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1) |
|---|
| IC50 | 315±n/a nM |
|---|
| Citation |  PubChem, PC Dose-response cell-based assay for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1) PubChem Bioassay(2007)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Steroidogenic factor 1 |
|---|
| Name: | Steroidogenic factor 1 |
|---|
| Synonyms: | AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP |
|---|
| Type: | Nuclear Hormone Receptor |
|---|
| Mol. Mass.: | 51643.43 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 461 |
|---|
| Sequence: | MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKT
QRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKL
ETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPL
AGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQV
RARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQN
CWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLA
LQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLL
LCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
|
|
|
|---|
| BDBM38962 |
|---|
| n/a |
|---|
| Name | BDBM38962 |
|---|
| Synonyms: | 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2,4-dione | 6-[4-(3-chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1H-pyrimidine-2,4-dione | 6-[4-(3-chlorophenyl)piperazin-1-yl]-3-cyclohexylpyrimidine-2,4(1H,3H)-dione | 6-[4-(3-chlorophenyl)piperazino]-3-cyclohexyl-uracil | MLS000094380 | SMR000029966 | cid_3238389 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H25ClN4O2 |
|---|
| Mol. Mass. | 388.891 |
|---|
| SMILES | Clc1cccc(c1)N1CCN(CC1)c1cc(=O)n(C2CCCCC2)c(=O)[nH]1 |
|---|
| Structure | 
|
|---|
Search and Browse
