BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetSteroidogenic factor 1
LigandBDBM39017
Substrate/Competitorn/a
Meas. Tech.Dose-response cell-based assay for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1)
IC50>11000±n/a nM
Citation PubChem, PC Dose-response cell-based assay for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1) PubChem Bioassay(2007)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Steroidogenic factor 1
Name:Steroidogenic factor 1
Synonyms:AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:Nuclear Hormone Receptor
Mol. Mass.:51643.43
Organism:Homo sapiens (Human)
Description:n/a
Residue:461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKT
QRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKL
ETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPL
AGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQV
RARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQN
CWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLA
LQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLL
LCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM39017
n/a
NameBDBM39017
Synonyms:(E)-3-[4-(dimethylamino)anilino]-1-phenyl-2-propen-1-one | (E)-3-[4-(dimethylamino)anilino]-1-phenyl-prop-2-en-1-one | (E)-3-[4-(dimethylamino)anilino]-1-phenylprop-2-en-1-one | (E)-3-[[4-(dimethylamino)phenyl]amino]-1-phenyl-prop-2-en-1-one | 3-{[4-(dimethylamino)phenyl]amino}-1-phenyl-2-propen-1-one | MLS000088290 | SMR000072535 | cid_2188632
TypeSmall organic molecule
Emp. Form.C17H18N2O
Mol. Mass.266.3376
SMILESCN(C)c1ccc(cc1)N=CCC(=O)c1ccccc1 |w:9.9|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: