| Reaction Details |
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 | Report a problem with these data |
| Target | Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) |
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| Ligand | BDBM39051 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose-response cell-based assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA) |
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| IC50 | >407±n/a nM |
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| Citation |  PubChem, PC Dose-response cell-based assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA) PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) |
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| Name: | Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) |
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| Synonyms: | NR1F1 | Nuclear receptor ROR-alpha | Nuclear receptor ROR-alpha (Alpha-2) | Nuclear receptor ROR-alpha (Retinoid-related orphan receptor-alpha) (Nuclear receptor RZR-alpha). | RORA | RORA_HUMAN | RZRA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 63033.59 |
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| Organism: | Homo sapiens (Human) |
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| Description: | EBI_101591 |
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| Residue: | 556 |
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| Sequence: | MNEGAPGDSDLETEARVPWSIMGHCLRTGQARMSATPTPAGEGARRDELFGILQILHQCI
LSSGDAFVLTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIEIIPCKICGDKSSGIHYGV
ITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGR
MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGH
TPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPT
VSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKI
TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYAS
PDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQ
KIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLY
KELFTSEFEPAMQIDG
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| BDBM39051 |
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| n/a |
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| Name | BDBM39051 |
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| Synonyms: | 4-(1-azepanyl)-1-(4-chlorophenyl)pyrazolo[3,4-d]pyrimidine | 4-(azepan-1-yl)-1-(4-chlorophenyl)pyrazolo[3,4-d]pyrimidine | MLS000100816 | SMR000017482 | cid_3702591 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H18ClN5 |
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| Mol. Mass. | 327.811 |
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| SMILES | Clc1ccc(cc1)-n1ncc2c(ncnc12)N1CCCCCC1 |
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| Structure | 
|
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