Reaction Details |
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Target | Steroidogenic factor 1 |
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Ligand | BDBM38913 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Counterscreen for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1) |
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IC50 | 1105±n/a nM |
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Citation | PubChem, PC Counterscreen for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1) PubChem Bioassay(2007)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Steroidogenic factor 1 |
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Name: | Steroidogenic factor 1 |
Synonyms: | AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP |
Type: | Nuclear Hormone Receptor |
Mol. Mass.: | 51643.43 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 461 |
Sequence: | MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKT
QRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKL
ETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPL
AGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQV
RARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQN
CWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLA
LQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLL
LCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
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BDBM38913 |
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n/a |
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Name | BDBM38913 |
Synonyms: | 3-[3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl]-N,N-dimethyl-propanamide | 3-[3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl]-N,N-dimethyl-propionamide | 3-[3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl]-N,N-dimethylpropanamide | MLS000042454 | SMR000046865 | cid_665578 |
Type | Small organic molecule |
Emp. Form. | C17H23N3O2 |
Mol. Mass. | 301.3834 |
SMILES | CN(C)C(=O)CCc1nc(no1)-c1ccc(cc1)C(C)(C)C |
Structure |
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