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TargetSteroidogenic factor 1
LigandBDBM37025
Substrate/Competitorn/a
Meas. Tech.Counterscreen for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1)
IC50 1441±n/a nM
Citation PubChem, PC Counterscreen for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1) PubChem Bioassay(2007)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Steroidogenic factor 1
Name:Steroidogenic factor 1
Synonyms:AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:Nuclear Hormone Receptor
Mol. Mass.:51643.43
Organism:Homo sapiens (Human)
Description:n/a
Residue:461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKT
QRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKL
ETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPL
AGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQV
RARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQN
CWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLA
LQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLL
LCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
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  Blast E-value cutoff:
BDBM37025
n/a
NameBDBM37025
Synonyms:4-[4-[2-(4-chloranylphenoxy)ethyl]piperazin-1-yl]thieno[2,3-d]pyrimidine | 4-[4-[2-(4-chlorophenoxy)ethyl]-1-piperazinyl]thieno[2,3-d]pyrimidine | 4-[4-[2-(4-chlorophenoxy)ethyl]piperazin-1-yl]thieno[2,3-d]pyrimidine | 4-[4-[2-(4-chlorophenoxy)ethyl]piperazino]thieno[2,3-d]pyrimidine | MLS000056574 | SMR000064686 | cid_2537908
TypeSmall organic molecule
Emp. Form.C18H19ClN4OS
Mol. Mass.374.888
SMILESClc1ccc(OCCN2CCN(CC2)c2ncnc3sccc23)cc1
Structure
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