| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-related protein A1 |
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| Ligand | BDBM34188 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | TR-FRET secondary assay for HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1 |
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| IC50 | 1460±200 nM |
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| Citation |  PubChem, PC TR-FRET secondary assay for HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1 PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Bcl-2-related protein A1 |
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| Name: | Bcl-2-related protein A1 |
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| Synonyms: | A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1 |
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| Type: | Apoptosis regulator protein |
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| Mol. Mass.: | 19909.74 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | gi_11024684 |
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| Residue: | 172 |
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| Sequence: | MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFH
VESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSS
FVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
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| BDBM34188 |
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| n/a |
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| Name | BDBM34188 |
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| Synonyms: | 2-[4-(4-fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-yl]sulfonylacetic acid ethyl ester | 2-[[4-(4-fluorophenyl)-6-(trifluoromethyl)-2-pyrimidinyl]sulfonyl]acetic acid ethyl ester | MLS000100272 | SMR000082310 | cid_2980973 | ethyl 2-[4-(4-fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-yl]sulfonylacetate | ethyl 2-[4-(4-fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-yl]sulfonylethanoate | ethyl {[4-(4-fluorophenyl)-6-(trifluoromethyl)-2-pyrimidinyl]sulfonyl}acetate |
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| Type | Small organic molecule |
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| Emp. Form. | C15H12F4N2O4S |
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| Mol. Mass. | 392.325 |
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| SMILES | CCOC(=O)CS(=O)(=O)c1nc(cc(n1)C(F)(F)F)-c1ccc(F)cc1 |
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| Structure | 
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