| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Bcl-2-related protein A1 |
|---|
| Ligand | BDBM39143 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | TR-FRET secondary assay for HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1 |
|---|
| IC50 | 1450±110 nM |
|---|
| Citation |  PubChem, PC TR-FRET secondary assay for HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1 PubChem Bioassay(2008)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Bcl-2-related protein A1 |
|---|
| Name: | Bcl-2-related protein A1 |
|---|
| Synonyms: | A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1 |
|---|
| Type: | Apoptosis regulator protein |
|---|
| Mol. Mass.: | 19909.74 |
|---|
| Organism: | Mus musculus (Mouse) |
|---|
| Description: | gi_11024684 |
|---|
| Residue: | 172 |
|---|
| Sequence: | MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFH
VESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSS
FVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
|
|
|
|---|
| BDBM39143 |
|---|
| n/a |
|---|
| Name | BDBM39143 |
|---|
| Synonyms: | 3-chloranyl-1-(2-chlorophenyl)-4-(4-methylpiperazin-1-yl)pyrrole-2,5-dione | 3-chloro-1-(2-chlorophenyl)-4-(4-Methylpiperazin-1-yl)-1H-pyrrole-2,5-dione | 3-chloro-1-(2-chlorophenyl)-4-(4-methyl-1-piperazinyl)pyrrole-2,5-dione | 3-chloro-1-(2-chlorophenyl)-4-(4-methylpiperazin-1-yl)pyrrole-2,5-dione | 3-chloro-1-(2-chlorophenyl)-4-(4-methylpiperazino)-3-pyrroline-2,5-quinone | CHEMBL1271825 | MLS-0090833.0001 | cid_16654640 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H15Cl2N3O2 |
|---|
| Mol. Mass. | 340.205 |
|---|
| SMILES | CN1CCN(CC1)C1=C(Cl)C(=O)N(C1=O)c1ccccc1Cl |c:8| |
|---|
| Structure | 
|
|---|
Search and Browse
