| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 1 |
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| Ligand | BDBM31700 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Cdc25B Catalytic Domain Protein Tyrosine Phosphatase Probe Assessment: MKP-1 Dose Response Selectivity comparison. |
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| IC50 | 7018±n/a nM |
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| Citation |  PubChem, PC Cdc25B Catalytic Domain Protein Tyrosine Phosphatase Probe Assessment: MKP-1 Dose Response Selectivity comparison. PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Dual specificity protein phosphatase 1 |
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| Name: | Dual specificity protein phosphatase 1 |
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| Synonyms: | CL100 | DUS1_HUMAN | DUSP1 | Dual specificity protein phosphatase hVH1 | MAP kinase phosphatase 1 | MKP-1 | MKP1 | PTPN10 | Protein-tyrosine phosphatase CL100 | VH1 |
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| Type: | Protein phosphatase |
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| Mol. Mass.: | 39301.48 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_4758204 |
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| Residue: | 367 |
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| Sequence: | MVMEVGTLDAGGLRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAM
GLEHIVPNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFF
LKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPF
LYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEA
IDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFS
FMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSP
ITTSPSC
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| BDBM31700 |
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| n/a |
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| Name | BDBM31700 |
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| Synonyms: | (5Z)-5-(5-bromo-2-methoxybenzylidene)-2-(2-furyl)[1,3]thiazolo[3,2-b][1,2,4]triazol-6(5H)-one | 5-(5-bromo-2-methoxy-benzylidene)-2-(2-furyl)thiazolo[3,2-b][1,2,4]triazol-6-one | 5-[(5-bromanyl-2-methoxy-phenyl)methylidene]-2-(furan-2-yl)-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one | 5-[(5-bromo-2-methoxyphenyl)methylidene]-2-(2-furanyl)-6-thiazolo[3,2-b][1,2,4]triazolone | 5-[(5-bromo-2-methoxyphenyl)methylidene]-2-(furan-2-yl)-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one | MLS000043560 | SMR000020576 | cid_3236807 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H10BrN3O3S |
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| Mol. Mass. | 404.238 |
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| SMILES | COc1ccc(Br)cc1C=c1sc2nc(nn2c1=O)-c1ccco1 |
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| Structure | 
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