| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM39823 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| pH | 7±0 |
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| Ki | 7.0e+2±n/a nM |
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| Citation |  Tondi, D; Powers, RA; Caselli, E; Negri, MC; Blázquez, J; Costi, MP; Shoichet, BK Structure-based design and in-parallel synthesis of inhibitors of AmpC beta-lactamase. Chem Biol8:593-611 (2001) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | AMPC_ECOLI | Beta-lactamase | Beta-lactamase (AmpC) | Beta-lactamase AmpC | Cephalosporinase | Escherichia coli K-12 | ampA | ampC |
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| Type: | Protien |
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| Mol. Mass.: | 41561.62 |
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| Organism: | Escherichia coli |
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| Description: | P00811 |
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| Residue: | 377 |
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| Sequence: | MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWG
YADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPTTKYWPELTAKQWNGI
TLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVK
PSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVK
STIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSII
NGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNY
PNPARVDAAWQILNALQ
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| BDBM39823 |
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| n/a |
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| Name | BDBM39823 |
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| Synonyms: | Amide and sulfonamide derivatives, 7 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H11BF3NO5S |
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| Mol. Mass. | 361.101 |
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| SMILES | OB(O)c1cccc(NS(=O)(=O)c2ccc(OC(F)(F)F)cc2)c1 |
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| Structure | 
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