Ki Summary

Reaction Details

Report a problem with these data

Target

Mothers against decapentaplegic homolog 3

Ligand

BDBM40307

Substrate/Competitor

n/a

Meas. Tech.

SMAD Transcription Factor Inhibitors Dose Response Confirmation

IC50

11110±n/a nM

Citation

PubChem, PC SMAD Transcription Factor Inhibitors Dose Response Confirmation PubChem Bioassay(2007)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Mothers against decapentaplegic homolog 3

Name:

Mothers against decapentaplegic homolog 3

Synonyms:

MADH3 | SMAD3 | SMAD3_HUMAN

Type:

Enzyme Catalytic Domain

Mol. Mass.:

48085.78

Organism:

Homo sapiens (Human)

Description:

gi_5174513

Residue:

425

Sequence:

MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV
NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV
CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP
PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL
NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG
GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF
EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR
CSSVS

BDBM40307

n/a

Name

BDBM40307

Synonyms:

MLS000046472 | N-(3-azepan-1-ylpropyl)-1-[2-(4-methylphenyl)ethyl]-5-oxopyrrolidine-3-carboxamide | N-[3-(1-azepanyl)propyl]-1-[2-(4-methylphenyl)ethyl]-5-oxo-3-pyrrolidinecarboxamide | N-[3-(azepan-1-yl)propyl]-1-[2-(4-methylphenyl)ethyl]-5-oxidanylidene-pyrrolidine-3-carboxamide | N-[3-(azepan-1-yl)propyl]-1-[2-(4-methylphenyl)ethyl]-5-oxopyrrolidine-3-carboxamide | N-[3-(azepan-1-yl)propyl]-5-keto-1-[2-(p-tolyl)ethyl]pyrrolidine-3-carboxamide | SMR000032483 | cid_3237466

Type

Small organic molecule

Emp. Form.

C23H35N3O2

Mol. Mass.

385.5429

SMILES

Cc1ccc(CCN2CC(CC2=O)C(=O)NCCCN2CCCCCC2)cc1

Structure