| Reaction Details |
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 | Report a problem with these data |
| Target | Mothers against decapentaplegic homolog 3 |
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| Ligand | BDBM50099737 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SMAD Transcription Factor Inhibitors Dose Response Confirmation |
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| IC50 | 9894±n/a nM |
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| Citation |  PubChem, PC SMAD Transcription Factor Inhibitors Dose Response Confirmation PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Mothers against decapentaplegic homolog 3 |
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| Name: | Mothers against decapentaplegic homolog 3 |
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| Synonyms: | MADH3 | SMAD3 | SMAD3_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 48085.78 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_5174513 |
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| Residue: | 425 |
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| Sequence: | MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV
NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV
CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP
PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL
NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG
GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF
EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR
CSSVS
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| BDBM50099737 |
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| n/a |
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| Name | BDBM50099737 |
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| Synonyms: | 2-Amino-phenanthrene-9,10-dione | CHEMBL417727 | US9073941, 902 | cid_254021 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H9NO2 |
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| Mol. Mass. | 223.2268 |
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| SMILES | Nc1ccc-2c(c1)C(=O)C(=O)c1ccccc-21 |
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| Structure | 
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