Reaction Details |
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Target | fMet-Leu-Phe receptor |
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Ligand | BDBM40411 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay |
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Ki | 6000±n/a nM |
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Citation | PubChem, PC Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay PubChem Bioassay(2007)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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fMet-Leu-Phe receptor |
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Name: | fMet-Leu-Phe receptor |
Synonyms: | FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 38456.14 |
Organism: | Homo sapiens (Human) |
Description: | gi_4503779 |
Residue: | 350 |
Sequence: | METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVT
TISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIA
LDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNF
SPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPL
RVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPML
YVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
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BDBM40411 |
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n/a |
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Name | BDBM40411 |
Synonyms: | (4E)-5-(2,5-dimethoxyphenyl)-4-[hydroxy(phenyl)methylene]-1-(3-pyridyl)pyrrolidine-2,3-quinone | (4E)-5-(2,5-dimethoxyphenyl)-4-[hydroxy(phenyl)methylidene]-1-(3-pyridinyl)pyrrolidine-2,3-dione | (4E)-5-(2,5-dimethoxyphenyl)-4-[hydroxy(phenyl)methylidene]-1-pyridin-3-ylpyrrolidine-2,3-dione | (4E)-5-(2,5-dimethoxyphenyl)-4-[oxidanyl(phenyl)methylidene]-1-pyridin-3-yl-pyrrolidine-2,3-dione | UNM000003538701 | cid_5291451 |
Type | Small organic molecule |
Emp. Form. | C24H20N2O5 |
Mol. Mass. | 416.426 |
SMILES | COc1ccc(OC)c(c1)C1C(C(=O)c2ccccc2)C(=O)C(=O)N1c1cccnc1 |
Structure |
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