| Reaction Details |
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 | Report a problem with these data |
| Target | fMet-Leu-Phe receptor |
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| Ligand | BDBM40418 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay |
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| Ki | 2900±n/a nM |
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| Citation |  PubChem, PC Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| fMet-Leu-Phe receptor |
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| Name: | fMet-Leu-Phe receptor |
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| Synonyms: | FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 38456.14 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_4503779 |
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| Residue: | 350 |
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| Sequence: | METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVT
TISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIA
LDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNF
SPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPL
RVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPML
YVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
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| BDBM40418 |
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| n/a |
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| Name | BDBM40418 |
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| Synonyms: | 2-(2,4-dimethoxyphenyl)-1-(2-morpholin-4-ylethyl)-4-oxidanyl-3-thiophen-2-ylcarbonyl-2H-pyrrol-5-one | 2-(2,4-dimethoxyphenyl)-4-hydroxy-1-(2-morpholin-4-ylethyl)-3-(thiophene-2-carbonyl)-2H-pyrrol-5-one | 2-(2,4-dimethoxyphenyl)-4-hydroxy-1-[2-(4-morpholinyl)ethyl]-3-[oxo(thiophen-2-yl)methyl]-2H-pyrrol-5-one | 5-(2,4-dimethoxyphenyl)-3-hydroxy-1-(2-morpholinoethyl)-4-(2-thenoyl)-3-pyrrolin-2-one | UNM000003551201 | cid_15996528 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H26N2O6S |
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| Mol. Mass. | 458.527 |
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| SMILES | COc1ccc(C2C(C(=O)c3cccs3)C(=O)C(=O)N2CCN2CCOCC2)c(OC)c1 |
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| Structure | 
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