| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Heat shock 70 kDa protein 1A |
|---|
| Ligand | BDBM31696 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | TR-FRET secondary assay for HTS discovery of chemical inhibitors of Hsp70 |
|---|
| IC50 | 16000±1200 nM |
|---|
| Citation |  PubChem, PC TR-FRET secondary assay for HTS discovery of chemical inhibitors of Hsp70 PubChem Bioassay(2008)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Heat shock 70 kDa protein 1A |
|---|
| Name: | Heat shock 70 kDa protein 1A |
|---|
| Synonyms: | HSPA1A | Heat Shock 70kDa Protein 1 | V9GZ37_HUMAN | heat shock 70kDa protein 1A |
|---|
| Type: | ATP-binding protein |
|---|
| Mol. Mass.: | 51937.99 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_123271505; GST-tagged ATPase domain |
|---|
| Residue: | 476 |
|---|
| Sequence: | MAKAAAIGIDLGTTYSCVGVFQHGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGD
THLGGEDFDNRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEID
SLFEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPK
VQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLET
AGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIP
PAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKY
KAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANT
LAEKDEFEHKRKELEQVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD
|
|
|
|---|
| BDBM31696 |
|---|
| n/a |
|---|
| Name | BDBM31696 |
|---|
| Synonyms: | 2-[4-[3,9-bis(oxidanylidene)-2-(oxolan-2-ylmethyl)-1H-chromeno[2,3-c]pyrrol-1-yl]phenoxy]ethanamide | 2-[4-[3,9-diketo-2-(tetrahydrofurfuryl)-1H-chromeno[2,3-c]pyrrol-1-yl]phenoxy]acetamide | 2-[4-[3,9-dioxo-2-(2-oxolanylmethyl)-1H-[1]benzopyrano[2,3-c]pyrrol-1-yl]phenoxy]acetamide | 2-[4-[3,9-dioxo-2-(oxolan-2-ylmethyl)-1H-chromeno[2,3-c]pyrrol-1-yl]phenoxy]acetamide | MLS000041605 | SMR000044166 | cid_663437 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H22N2O6 |
|---|
| Mol. Mass. | 434.4413 |
|---|
| SMILES | NC(=O)COc1ccc(cc1)C1N(CC2CCCO2)C(=O)c2oc3ccccc3c(=O)c12 |
|---|
| Structure | 
|
|---|
Search and Browse
