| Reaction Details |
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 | Report a problem with these data |
| Target | Heat shock 70 kDa protein 1A |
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| Ligand | BDBM31709 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | TR-FRET secondary assay for HTS discovery of chemical inhibitors of Hsp70 |
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| IC50 | >100000±0 nM |
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| Citation |  PubChem, PC TR-FRET secondary assay for HTS discovery of chemical inhibitors of Hsp70 PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Heat shock 70 kDa protein 1A |
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| Name: | Heat shock 70 kDa protein 1A |
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| Synonyms: | HSPA1A | Heat Shock 70kDa Protein 1 | V9GZ37_HUMAN | heat shock 70kDa protein 1A |
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| Type: | ATP-binding protein |
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| Mol. Mass.: | 51937.99 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_123271505; GST-tagged ATPase domain |
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| Residue: | 476 |
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| Sequence: | MAKAAAIGIDLGTTYSCVGVFQHGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGD
THLGGEDFDNRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEID
SLFEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPK
VQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLET
AGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIP
PAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKY
KAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANT
LAEKDEFEHKRKELEQVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD
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| BDBM31709 |
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| n/a |
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| Name | BDBM31709 |
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| Synonyms: | 4-amino-2-phenyl-isoindoline-1,3-quinone | 4-amino-2-phenylisoindole-1,3-dione | 4-azanyl-2-phenyl-isoindole-1,3-dione | CHEMBL269410 | MLS000104009 | SMR000015725 | cid_3448473 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H10N2O2 |
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| Mol. Mass. | 238.2414 |
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| SMILES | Nc1cccc2C(=O)N(C(=O)c12)c1ccccc1 |
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| Structure | 
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