| Reaction Details |
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 | Report a problem with these data |
| Target | Complement C1s subcomponent |
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| Ligand | BDBM32761 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Complement factor C1s IC50 from mixture screen |
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| IC50 | 11260±2970 nM |
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| Citation |  PubChem, PC Complement factor C1s IC50 from mixture screen PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Complement C1s subcomponent |
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| Name: | Complement C1s subcomponent |
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| Synonyms: | C1 esterase | C1S | C1S_HUMAN | Complement C1s | Complement C1s subcomponent | Complement C1s subcomponent heavy chain | Complement C1s subcomponent light chain | Complement component 1 subcomponent s | Trypsin | complement component 1, s subcomponent |
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| Type: | Protein |
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| Mol. Mass.: | 76657.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P09871 |
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| Residue: | 688 |
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| Sequence: | MWCIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIE
LSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERF
TGFAAYYVATDINECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVF
TALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVF
VAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDTP
NSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCG
IPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPK
CVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNPWAGGALINEYWVLTAAHVVEGN
REPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVK
MGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKV
EKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCG
TYGLYTRVKNYVDWIMKTMQENSTPRED
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| BDBM32761 |
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| n/a |
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| Name | BDBM32761 |
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| Synonyms: | 2-furancarboxylic acid [5-amino-1-(4-methoxyphenyl)sulfonyl-3-pyrazolyl] ester | Furan-2-carboxylic acid 5-amino-1-(4-methoxy-benzenesulfonyl)-1H-pyrazol-3-yl ester | MLS000033887 | SMR000014916 | US11584714, Compound 40# | [5-amino-1-(4-methoxyphenyl)sulfonylpyrazol-3-yl] furan-2-carboxylate | [5-azanyl-1-(4-methoxyphenyl)sulfonyl-pyrazol-3-yl] furan-2-carboxylate | cid_653862 | furan-2-carboxylic acid [5-amino-1-(4-methoxyphenyl)sulfonyl-pyrazol-3-yl] ester |
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| Type | Small organic molecule |
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| Emp. Form. | C15H13N3O6S |
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| Mol. Mass. | 363.345 |
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| SMILES | COc1ccc(cc1)S(=O)(=O)n1nc(OC(=O)c2ccco2)cc1N |
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| Structure | 
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