| Reaction Details |
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 | Report a problem with these data |
| Target | Complement C1s subcomponent |
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| Ligand | BDBM32671 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Complement factor C1s IC50 from mixture screen |
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| IC50 | 880±120 nM |
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| Citation |  PubChem, PC Complement factor C1s IC50 from mixture screen PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Complement C1s subcomponent |
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| Name: | Complement C1s subcomponent |
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| Synonyms: | C1 esterase | C1S | C1S_HUMAN | Complement C1s | Complement C1s subcomponent | Complement C1s subcomponent heavy chain | Complement C1s subcomponent light chain | Complement component 1 subcomponent s | Trypsin | complement component 1, s subcomponent |
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| Type: | Protein |
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| Mol. Mass.: | 76657.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P09871 |
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| Residue: | 688 |
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| Sequence: | MWCIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIE
LSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERF
TGFAAYYVATDINECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVF
TALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVF
VAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDTP
NSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCG
IPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPK
CVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNPWAGGALINEYWVLTAAHVVEGN
REPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVK
MGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKV
EKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCG
TYGLYTRVKNYVDWIMKTMQENSTPRED
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| BDBM32671 |
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| n/a |
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| Name | BDBM32671 |
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| Synonyms: | 3-(2-furyl)-5-(methylthio)-1-(2-thienylcarbonyl)-1H-1,2,4-triazole | MLS000063602 | SMR000075208 | [3-(2-furanyl)-5-(methylthio)-1,2,4-triazol-1-yl]-thiophen-2-ylmethanone | [3-(2-furyl)-5-(methylthio)-1,2,4-triazol-1-yl]-(2-thienyl)methanone | [3-(furan-2-yl)-5-methylsulfanyl-1,2,4-triazol-1-yl]-thiophen-2-yl-methanone | [3-(furan-2-yl)-5-methylsulfanyl-1,2,4-triazol-1-yl]-thiophen-2-ylmethanone | cid_976329 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H9N3O2S2 |
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| Mol. Mass. | 291.349 |
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| SMILES | CSc1nc(nn1C(=O)c1cccs1)-c1ccco1 |
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| Structure | 
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