| Reaction Details |
|---|
 | Report a problem with these data |
| Target | DNA-directed RNA polymerase subunit beta |
|---|
| Ligand | BDBM41199 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | RNA polymerase dose-response confirmation |
|---|
| IC50 | >50000±0 nM |
|---|
| Citation |  PubChem, PC RNA polymerase dose-response confirmation PubChem Bioassay(2008)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| DNA-directed RNA polymerase subunit beta |
|---|
| Name: | DNA-directed RNA polymerase subunit beta |
|---|
| Synonyms: | RNA polymerase beta subunit (EC 2.7.7.6) |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 150595.80 |
|---|
| Organism: | Escherichia coli |
|---|
| Description: | A0A0E2LB94 |
|---|
| Residue: | 1342 |
|---|
| Sequence: | MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQ
SYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQ
EVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYR
GSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQME
LVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKD
YIDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRL
SALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLREEIEGSGIL
SKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLS
LGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTR
ERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVT
DEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQV
VSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKR
GGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERG
DVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVS
RDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEK
LLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDL
SEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDE
LKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKIN
PIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAK
LREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLK
LGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLG
GKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMP
ESFNVLLKEIRSLGINIELEDE
|
|
|
|---|
| BDBM41199 |
|---|
| n/a |
|---|
| Name | BDBM41199 |
|---|
| Synonyms: | 2-(3,4-dimethoxyphenyl)-3-ethanoyl-1-(2-methoxyethyl)-4-oxidanyl-2H-pyrrol-5-one | 3-acetyl-2-(3,4-dimethoxyphenyl)-4-hydroxy-1-(2-methoxyethyl)-2H-pyrrol-5-one | 4-Acetyl-5-(3,4-dimethoxy-phenyl)-3-hydroxy-1-(2-methoxy-ethyl)-1,5-dihydro-pyrrol-2-one | 4-acetyl-5-(3,4-dimethoxyphenyl)-3-hydroxy-1-(2-methoxyethyl)-3-pyrrolin-2-one | MLS000077329 | SMR000012212 | cid_652689 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H21NO6 |
|---|
| Mol. Mass. | 335.3517 |
|---|
| SMILES | COCCN1C(C(C(C)=O)C(=O)C1=O)c1ccc(OC)c(OC)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
