Reaction Details | |||
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Report a problem with these data | |||
Target | P2X purinoceptor 3 | ||
Ligand | BDBM266712 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Human P2X3 Receptor Inhibition Assay | ||
pH | 7.5±n/a | ||
IC50 | 1.000±n/a nM | ||
Comments | extracted | ||
Citation | Kai, H; Horiguchi, T; Asahi, K; Fujii, Y Triazine derivative and pharmaceutical composition having an analgesic activity comprising the same US Patent US9718790 Publication Date 8/1/2017 | ||
More Info.: | Get all data from this article, Assay Method | ||
P2X purinoceptor 3 | |||
Name: | P2X purinoceptor 3 | ||
Synonyms: | ATP receptor | Glucocorticoid receptor | P2RX3 | P2RX3_HUMAN | P2X purinoceptor 3 | P2X purinoceptor 3 (P2RX3) | P2X purinoceptor 3 (P2X3) | P2X3 | P2X3 purinoceptor | Purinergic receptor | p2x3 + hsa | ||
Type: | Protein | ||
Mol. Mass.: | 44292.02 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P56373 | ||
Residue: | 397 | ||
Sequence: |
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BDBM266712 | |||
n/a | |||
Name | BDBM266712 | ||
Synonyms: | US9718790, I-2446 | ||
Type | Small organic molecule | ||
Emp. Form. | C24H26N6O3 | ||
Mol. Mass. | 446.5016 | ||
SMILES | C[C@H]1CC[C@H](Cn2c(=O)n(C)c(=O)[nH]\c2=N/c2ccc(Oc3cccc(n3)C#N)cc2)CC1 |r,wU:4.4,wD:1.0,(8.67,-6.55,;7.34,-5.78,;7.34,-4.24,;6,-3.47,;4.67,-4.24,;3.33,-3.47,;3.33,-1.93,;4.67,-1.16,;6,-1.93,;4.67,.38,;6,1.15,;3.33,1.15,;3.33,2.69,;2,.38,;2,-1.16,;.67,-1.93,;-.67,-1.16,;-.67,.38,;-2,1.15,;-3.33,.38,;-4.67,1.15,;-4.67,2.69,;-3.33,3.46,;-3.33,5,;-4.67,5.77,;-6,5,;-6,3.46,;-7.34,5.78,;-8.67,6.55,;-3.33,-1.16,;-2,-1.93,;4.67,-5.78,;6,-6.55,)| | ||
Structure |